Memory impairment and hippocampus specific protein oxidation induced by ethanol intake and 3, 4-Methylenedioxymethamphetamine (MDMA) in mice

the effect of glutathione on nephrotoxicity, induced from 3, 4-methylenedioxymethamphetamine (mdma) in mice

3,4-methylenedioxymethamphetamine (mdma) or ecstasy, has had a widely spread popularity among young adults in recent years. kidney toxicity is one of the consequences of ecstasy. the studies have shown that ecstasy is metabolized by cytochrome p450 to reactive electrophil metabolites which detoxify by glutathione (gsh) conjugation. to our knowledge in vivo study of the effect of glutathione on ...

Effects of Repeated Administration of 3,4-methylenedioxymethamphetamine (MDMA) on Avoidance Memory and Cell Density in Rats\' Hippocampus

Introduction MDMA or ecstasy is a derivative of amphetamines used mostly by young people worldwide. Although the acute effects of this drug are known, the effect of chronic administration is not well studied. Therefor the aim of this study was to determine the effects of repeated (long term) administration of MDMA on rats' memory and their hippocampal cell density. Method: Young adult male W...

Effects of Piperine Pretreatment on Antioxidant Capacity and Spatial Memory Impairment Induced by Local Injection of Lysolecethin in Rat Hippocampus

Background and purpose: Piperine as the main alkaloid of black pepper has antioxidant and neuroprotective properties, so, it is an appropriate candidate to be studied in animal models of multiple sclerosis. This research aimed at investigating the effect of pretreatment with piperine on spatial memory, oxidative stress, and myelin repair gene markers in local demyelination model. Materials and...

+ / - ) - 3 , 4 - methylenedioxymethamphetamine ( MDMA , “ Ecstasy ” ) Investigator ’ s Brochure

effects of repeated administration of 3,4-methylenedioxymethamphetamine (mdma) on avoidance memory and cell density in rats' hippocampus

introduction mdma or ecstasy is a derivative of amphetamines used mostly by young people worldwide. although the acute effects of this drug are known, the effect of chronic administration is not well studied. therefor the aim of this study was to determine the effects of repeated (long term) administration of mdma on rats' memory and their hippocampal cell density. method: young adult male...